Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice.

J Cachexia Sarcopenia Muscle · 2025 · PMC12134771 · PMID 40464222

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an increasing trendno p-value reported

Compared with the PBS group, serum P1NP levels showed an increasing trend in the Apc001OA and Apc001OA‐d6 groups, and CTX‐I levels appeared to decrease in these groups, but neither change reached statistical significance (Figure 1c ). 3.2.2.

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did not reach statistical significanceno p-value reported

The expression levels of Bglap and Runx2 in the Apc001OA and Apc001OA‐d6 groups showed an increasing trend compared with the PBS group, although they did not reach statistical significance (Figure 5d–e ).

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