Expression and clinical significance of programmed cell death protein 1/programmed death-ligand 1 in non-small cell lung cancer patients with rare mutations of epidermal growth factor receptor gene: A retrospective cohort study.

Cytojournal · 2025 · PMC12134896 · PMID 40469712

Europe PMC DOI

hedged sentences

0.0410

closest p · 0.8× alpha

0.0910

boldest claim

The sentences

marginally significantP = 0.041actually significant

Moreover, the OS was longer in the PN group (21.71 ± 5.82 months) than in the PP group (20.01 ± 5.18 months), although the difference was marginally significant (t = 2213.5, P = 0.041).

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borderline significanceP = 0.072so close (0.05 < p ≤ 0.1)

However, the distribution of pathological type (adenocarcinoma and squamous carcinoma) displayed borderline significance (c 2 = 3.230, P = 0.072), which suggests a potential trend warranting further investigation.

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did not reach statistical significanceP = 0.091so close (0.05 < p ≤ 0.1)

Similarly, a negative correlation was observed between PD-1 expression and OS, though it did not reach statistical significance (r = −0.154, R 2 = 0.024, P = 0.091).

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