An improved cytological assay for R-loop detection in Saccharomyces cerevisiae utilizing a catalytically inactive RNase H.

G3 (Bethesda) · 2025 · PMC12134985 · PMID 40205716

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near-significantno p-value reported

Drugs that caused significant increases in dRnh1-GFP focus-positive cells (aphidicolin, HU, and idarubicin) also caused near-significant increases in the Pearson's coefficient for dRnh1-GFP/S9.6 overlap ( Supplementary Fig. 6e ).

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