Causal association between plasma proteins and lung adenocarcinoma: a two-sample mendelian randomization study.

Notably, although PCYOX1 did not reach statistical significance in the external validation of the deCODE dataset ( P = 0.70), the post-MR meta-analysis still demonstrated a statistically significant combined effect for PCYOX1 due to the high weight contribution of the preliminary analysis (92.6% in the common effect model and 90.7% in the random effects model).

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