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The UNC5C T835M mutation associated with Alzheimer's disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice.

Mol Neurodegener · 2025 · PMC12135551 · PMID 40468412

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Both CL1 and CL2 levels were increased in Unc5c KI/KI mice, although CL1 did not reach statistical significance (Fig. 4 A, B).

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