Comparative Effectiveness of Rivastigmine and Donepezil in Patients With Alzheimer's Disease: A Retrospective Cohort Study.

Cureus · 2025 · PMC12135722 · PMID 40470403

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

near-significantp = 0.058so close (0.05 < p ≤ 0.1)

There appeared to be a near-significant effect on CSF amyloid levels (p = 0.058), which was not statistically significant.

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highly significantno p-value reported

The effect sizes for MMSE (d = 3.08, p < 0.001) and CSF biomarkers (d = 2.88, p < 0.001) were highly significant, suggesting large differences between groups in terms of cognitive function and disease pathology measures (Figure 5 ).

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