Elucidating Development Trajectories of Brain Functional Abnormalities in Major Depressive Disorder Utilizing a Data-Driven Disease Progression Model.

Hum Brain Mapp · 2025 · PMC12136716 · PMID 40467053

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did not reach statistical significanceno p-value reported

Although the clinical scores‐stage correlations did not reach statistical significance, the positive trends between CD scores and neuroimaging stages suggest that ALFF abnormality progression may partially reflect worsening clinical symptoms.

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