Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia.

Biochem Biophys Rep · 2025 · PMC12136894 · PMID 40469777

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an increasing trendno p-value reported

In addition, all tested drugs showed an increasing trend in CD47 mRNA expression.

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did not reach statistical significanceno p-value reported

Regarding CD200, ibrutinib demonstrated an elevation and venetoclax showed a decreasing in its mRNA expression; however, the outcomes did not reach statistical significance.

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