Distinct effects of global signal regression on brain activity during propofol and sevoflurane anesthesia.

Front Neurosci · 2025 · PMC12137232 · PMID 40474916

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showed a trendno p-value reported

Our results revealed that both propofol and sevoflurane administration showed a trend toward decreased ALFF from baseline to unconscious states ( Figure 2c ), though this decrease reached statistical significance only for propofol in withoutGS condition.

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an increasing trendno p-value reported

Some FC patterns even showed an increasing trend after LOC.

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