Reduction in myofilament Ca<sup>2+</sup> sensitivity partially ameliorates the cardiac phenotype in hypertrophic cardiomyopathy linked to a TnT-R92Q mutation.

Front Physiol · 2025 · PMC12141004 · PMID 40488145

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did not reach statistical significanceno p-value reported

However, this increase in RLC phosphorylation between DTG and TnT-R92Q mice did not reach statistical significance when we used Phos-Tag gels ( Supplementary Figure S3 ).

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Reduction in myofilament Ca&lt;sup&gt;2+&lt;/sup&gt; sensitivity partially ameliorates the cardiac phenotype in hypertrophic cardiomyopathy linked to a TnT-R92Q mutation.

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Reduction in myofilament Ca<sup>2+</sup> sensitivity partially ameliorates the cardiac phenotype in hypertrophic cardiomyopathy linked to a TnT-R92Q mutation.