Deficiency of myeloid NPC1 exacerbates liver injury and fibrosis by impairing macrophage efferocytosis.

J Adv Res · 2025 · PMC12147626 · PMID 39547438

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did not reach statistical significanceno p-value reported

Furthermore, ACs-treated Npc 1 ΔMφ BMDMs tended to have higher levels of Ccl2 and Tgfb1 mRNA, but lower levels of Tnf and Il10 mRNA than ACs-treated Npc1 WT BMDMs, although the difference did not reach statistical significance.

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