Similarly, 17.94 xenografts treated with the combination of actD and BTZ were significantly smaller than those who received vehicle control or BTZ alone ( Figures 4 C and 4D) (Although it did not reach statistical significance, tumor volume in the combination treatment cohort was also slightly smaller than the actD-only arm).
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Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor.
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