A Mutation in the Transmembrane Domain of Adenylate Cyclase 3 Impairs Enzymatic Function to Cause Sex-Specific Depression- and Anxiety-Like Behaviors and Food Seeking in a Rat Model.

Genes Brain Behav · 2025 · PMC12149762 · PMID 40492272

Europe PMC DOI

hedged sentence

0.0506

closest p · 1.0× alpha

0.0506

boldest claim

The sentences

nearly significantp = 0.0506so close (0.05 < p ≤ 0.1)

However, Adcy3 mut/mut females showed a slight decrease in lean mass that was nearly significant ( t 22 = 2.07, p = 0.0506; Figure 1E ), potentially explaining why there was not a significant body weight difference between WT and Adcy3 mut/mut females despite the large difference in fat mass.

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