examined CD25 expression in 88 pediatric ALK+ ALCL patients in a univariate analysis and found that patients with high CD25 ALK+ ALCL tended to have lower 5-year overall survival (OS) compared with those with low CD25 ALK+ ALCL; however, this difference did not reach statistical significance ( p = 0.05) [ 25 ].
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Low CD25 in ALK+ Anaplastic Large Cell Lymphoma Is Associated with Older Age, Thrombocytopenia, and Increased Expression of Surface CD3 and CD8.
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of borderline significancep = 0.05
In univariate analysis of pediatric ALK+ ALCL patients, high CD25 expression was associated with poorer clinical outcome, but this association was of borderline significance ( p = 0.05) [ 25 ].