In contrast, in early tumor shrinkage–negative patients on bevacizumab-based therapy showed a trend toward better overall survival, PFS, and postprogression survival outcomes compared with patients on anti-EGFR–based therapy (overall survival, HR = 1.22 [95% CI = 1.00 to 1.48]; PFS, HR = 1.27 [95% CI = 1.05 to 1.53]; postprogression survival, HR = 1.13 [95% CI = 0.90 to 1.43]).
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Associations between early tumor shrinkage/depth of response and survival from the ARCAD database.
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