Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction.

Mol Oncol · 2025 · PMC12161464 · PMID 39853696

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Indeed, many pro‐apoptotic genes downstream of the ATF4‐eIF2S1 pathway [ 64 ], such as DDIT3 and TRIB3 , showed a trend for increased expression upon TriC treatment.

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