Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage.

Front Genome Ed · 2025 · PMC12162470 · PMID 40520467

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did not reach statistical significanceno p-value reported

For Avpr1a , CRISPRi led to a modest but statistically significant reduction in expression, while CRISPRa effects were inconsistent and did not reach statistical significance.

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