Barely Significant
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The relationship between dietary flavonoid intake and hypertension: a cross-sectional study from NHANES.

Front Cardiovasc Med · 2025 · PMC12162475 · PMID 40520936

3
hedged sentences
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)
Flavanones showed a marginally significant trend ( p for trend =0.05), with the highest intake quartile approaching statistical significance (OR = 0 .74, 95% CI: 0.55–1.01, p = 0.06).

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highly significantno p-value reported
Hyperlipidemia status demonstrated a highly significant interaction effect ( p for interaction <0.0001), where individuals without hyperlipidemia (OR = 0 .75, 95%CI: 0.66–0.86) experienced a 25% reduction in hypertension risk from flavonoid intake, while those with hyperlipidemia (OR = 0 .99, 95%CI: 0.93–1.04) received virtually no protective benefit.

also in 132,142 other papers

showed a trendno p-value reported
Similarly, cardiovascular disease status showed a significant interaction ( p for interaction = 0.01), with those free of cardiovascular disease (OR = 0 .91, 95%CI: 0.86–0.96) demonstrating protective effects, whereas patients with cardiovascular disease (OR = 1 .26, 95%CI: 0.97–1.63) showed a trend toward increased risk, though not reaching statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.