Blood-brain barrier permeability in relation to disease severity and timing of multiple sclerosis diagnosis in optic neuritis.

Mult Scler J Exp Transl Clin · 2025 · PMC12163281 · PMID 40520967

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

did not reach statistical significancep = 0.068so close (0.05 < p ≤ 0.1)

29 Contrary to our previous publication 4 where NAWM BBB permeability predicted MS conversion according to the 2010 McDonald criteria, 15 NAWM BBB permeability did not reach statistical significance as an independent predictor of MS conversion according to the 2017 McDonald criteria (AUC = 0.652, p = 0.068).

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