Notwithstanding, it is worth noting that a lower proportion of SMAD4 (OR = 0.344, P = 0.108), NBEA (OR = 0.306, P = 0.132), and RNF43 (OR = 0.400, P = 0.409) mutations were found in peritoneal tumors and a higher proportion of HSPG2 (OR = 3.829, P = 0.248) mutations were found in PM, although these comparisons did not reach statistical significance ( Fig. 1D ).
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Spatial Heterogeneity, Stromal Phenotypes, and Therapeutic Vulnerabilities in Colorectal Cancer Peritoneal Metastasis.
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