STAT3 inhibition in combination with CD47 blockade inhibits osteosarcoma lung metastasis.

Front Immunol · 2025 · PMC12170595 · PMID 40529368

Europe PMC DOI

hedged sentence

0.0830

closest p · 1.7× alpha

0.0830

boldest claim

The sentences

did not reach statistical significancep =0.083so close (0.05 < p ≤ 0.1)

While there was a significant increase in MST in mice treated with combination therapy compared to those treated with WP1066 alone (p=0.027), the improvement in MST between mice treated with combination therapy versus anti-CD47 alone did not reach statistical significance (MST: 63 days vs 50 days, p =0.083).

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