Barely Significant
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Long-term outcomes of left atrial appendage closure techniques on stroke prevention of recurrent atrial fibrillation patients: epicardial excision versus percutaneous occlusion.

Front Cardiovasc Med · 2025 · PMC12174162 · PMID 40535146

1
hedged sentence
0.2700
closest p · 5.4× alpha
0.2700
boldest claim

The sentences

did not reach statistical significancep = 0.27not close (p > 0.1)
Although the adjusted analysis did not reach statistical significance ( p = 0.27), the hazard ratio of 0.48—indicating a 51.6% reduction in stroke risk with LAAC-EE compared to LAAC-PO—remains clinically important and merits further investigation in larger, prospective studies.

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