Barely Significant
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Multi-ancestry genome-wide association study of topiramate's effects on heavy alcohol use.

Alcohol Clin Exp Res (Hoboken) · 2025 · PMC12174493 · PMID 40322892

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nominally significantno p-value reported
Topiramate response PGS had nominally significant associations with lower rates of alcohol‐related liver disease, older age at alcohol use disorder diagnosis, and higher frequency of alcohol use.

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