Differences in survival were greater in magnitude among studies before 2010 but did not reach statistical significance among studies between 2010 and 2014 (HR 0.79, 95% CI 0.60–1.03; I 2 = 78%) or after 2015 (HR 0.91, 95% CI 0.79–1.04; I 2 = 89%).
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Impact of age on clinical outcomes among patients with hepatocellular carcinoma: A systematic review and meta-analysis.
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