Barely Significant
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Atrial dysfunction: a contrast-free marker for HFpEF in obese diabetics-insights from comprehensive CMR and serum biomarker analyses.

Cardiovasc Diabetol · 2025 · PMC12175437 · PMID 40533773

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failed to reach significanceno p-value reported
Among serum biomarkers, the association of Galectin-3 (OR 1.17, 95% CI 0.94–1.52, p = 0.183) and Pentraxin-3 (OR 3.34, 95% CI 0.92–15.7, p = 0.085) with HFpEF weakened and failed to reach significance in the adjusted model.

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In fact, the difference in between the HFpEF with T2DM group and the other subgroups did not reach statistical significance, with mean MPR values across all subgroups exceeding values observed by Arnold et al., who also demonstrated the prognostic relevance of reduced MPR in HFpEF patients [ 33 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.