The genetics of low and high birthweight and their relationship with cardiometabolic disease.

Nevertheless, the low-frequency allele also showed nominally significant association with increased risk of gestational diabetes mellitus and type 2 diabetes in publicly available FinnGen data [ 33 ] (gestational diabetes: logistic β=0.619 per addition of the minor G allele, SE=0.166, p =2×10 −4 ; type 2 diabetes: logistic β=0.299 per addition of the minor G allele, SE=0.070, p =2×10 −5 ), and decreased (inverse rank normal transformed) glucose levels ( p =1.9×10 −4 ), but not type 2 diabetes, HbA 1c or offspring birthweight (all p >0.05), in publicly available GWAS summary statistics from the UKBB published on the Neale website ( https://www.nealelab.is/ ).

also in 7,732 other papers