Barely Significant
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Tolerance in Thalamic Paraventricular Nucleus Neurons Following Chronic Treatment of Animals with Morphine.

eNeuro · 2025 · PMC12177709 · PMID 40456612

Europe PMCDOI
1
hedged sentence
0.0065
closest p · 0.1× alpha
0.0065
boldest claim

The sentences

did not reach statistical significancep = 0.0065actually significant
The morphine-dependent current in slices from morphine-treated animals (MTA) was significantly decreased relative to that in slices from untreated controls in AM- and NAc-projecting neurons; there was a trend in mPFC-projecting cells that did not reach statistical significance (AM-Naive: 33.1 ± 5.7, MTA: 11.7 ± 2.7, p = 0.0065, n Naive = 9 from 4 animals, n MTA = 6 from 4 animals; NAc-Naive: 36.7 ± 3.8, MTA: 19.2 ± 2.8, p = 0. 0.0177, n Naive = 8 from 4 animals, n MTA = 9 from 4 animals; mPFC-Naive: 34.3 ± 4.0, MTA: 18.6 ± 3.0, p = 0.0714, n Naive = 7 from 7 animals, n MTA = 9 from 3 animals, 2-way ANOVA with Tukey's test; Fig. 5 A , B ).

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