CHEK1 variant is a risk factor for premature ovarian insufficiency by mis- regulating metabolism and inflammation-related genes.

Hum Genomics · 2025 · PMC12178055 · PMID 40533835

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a decreasing trendno p-value reported

The mean fluorescent intensity (MFI) of GFP stained Tag showed a decreasing trend in MUT group compared to WT, but is not statistically significant (Fig. 1 D).

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showed a trendno p-value reported

Under identical experimental conditions, overexpression of the mutant CHEK1 in 293FT cells showed a trend of reduced protein expression compared to the wild-type.

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