<i>BDNF</i> Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults.

Moderated mediation analyses examining GFAP on cognitive outcomes did not reach statistical significance for females (memory z‐scores: nVal/Val = 44, nMet = 27, index of mod‐med = –0.14, 95% CI: –2.94 to 0.75; executive function z‐scores: nVal/Val = 45, nMet = 31, index of mod‐med = 0.06, 95% CI: –0.92 to 2.22) or males (memory z‐scores: nVal/Val = 28, nMet = 22, index of mod‐med = 0.07, 95% CI: –2.38 to 5.35; executive function z‐scores: nVal/Val = 30, nMet = 24, index of mod‐med = −1.10, 95% CI: –3.09 to 0.45). 3.

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