Integrated analysis of myeloperoxidase in gastric health and cancer: associations with pepsinogen levels, immune regulation, and prognosis in a large healthy population-based and TCGA cohorts.

Front Immunol · 2025 · PMC12179060 · PMID 40547041

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hedged sentences

0.0280

closest p · 0.6× alpha

0.0280

boldest claim

The sentences

a decreasing trendP = 0.028actually significant

Systolic blood pressure (SBP) showed a decreasing trend across quartiles (P = 0.028).

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did not reach statistical significanceno p-value reported

Multivariate analysis confirmed MPO as an independent prognostic factor for OS (HR = 2.781, 95% CI: 1.463–5.285, P = 0.002) and DSS (HR = 3.667, 95% CI: 1.704–7.890, P < 0.001), although its association with PFI did not reach statistical significance ( Figures 5A-F , Supplementary Tables 4-6 ).

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