Impact of antiphospholipid antibodies on heart valve involvements in systemic lupus erythematosus: based on CSTAR cohort.

Mohammed et al observed that patients with SLE with APS had a higher frequency of valve regurgitation compared with those without APS, although the difference did not reach statistical significance. 29 Similarly, Higuera et al found no significant association between classical aPLs and severe mitral regurgitation; however, the study did not evaluate the relationship between aPLs and mild, moderate or overall degrees of regurgitation, thereby limiting the interpretation of its findings. 31 Amo

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