A new approach combining a whole-slide foundation model and gradient boosting for predicting BRAF mutation status in dermatopathology.

Comput Struct Biotechnol J · 2025 · PMC12182775 · PMID 40547452

Europe PMC DOI

hedged sentence

0.1830

closest p · 3.7× alpha

0.1830

boldest claim

The sentences

failed to reach statistical significancep = 0.183not close (p > 0.1)

In particular, a DeLong comparison of AUCs on the independent UHE cohort (n = 68) failed to reach statistical significance (two-sided p = 0.183), likely reflecting insufficient power rather than true equivalence.

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