Targeting SLFN11-regulated pathways restores chemotherapy sensitivity in AML.

Blood Neoplasia · 2024 · PMC12182837 · PMID 40552140

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SLFN11 -high AML blasts showed a trend toward decreased colony formation with increasing doses of AraC, whereas AraC treatment showed significantly lower inhibitory effects for SLFN11 -low AML blasts ( Figure 3 D, left panel; P = .043).

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