Effects of semaglutide on metabolism and gut microbiota in high-fat diet-induced obese mice.

Front Pharmacol · 2025 · PMC12183439 · PMID 40552153

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showed a trendno p-value reported

Additionally, the MT group showed a significant increase in the expression level of Pgc1α in eWAT, while the FMT group only showed a trend of increase without significant difference ( Figure 3F ).

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a decreasing trendno p-value reported

Overall, the semaglutide intervention groups showed a decreasing trend in TC, LDL-C, and HDL-C levels compared to the HFD group, but without significant differences ( Figure 1K ).

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