Barely Significant
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Impact of positive airway pressure on right ventricular afterload in pulmonary arterial hypertension.

ERJ Open Res · 2025 · PMC12183734 · PMID 40551801

2
hedged sentences
0.0550
closest p · 1.1× alpha
0.0550
boldest claim

The sentences

a trend towards significancep=0.055so close (0.05 < p ≤ 0.1)
There was a trend towards significance for the main effect of time (Control versus CPAP; p=0.055 and interaction between group (PAH versus healthy individuals) and time (p=0.055) for oxygen saturation suggestive of an increase in oxygen saturation with CPAP of ∼1% (96.5±2.6 versus 97.4±1.9%) in PAH patients; however, not clinically significant.

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Among healthy participants, although the increase in PVR was small in absolute terms and did not reach statistical significance per se .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.