Dosimetric comparison and prognostic analysis of helical tomotherapy vs. intensity-modulated radiation therapy in locally advanced cervical cancer.

Oncol Lett · 2025 · PMC12183781 · PMID 40552253

Europe PMC DOI

hedged sentences

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

a nonsignificant trendP=0.089so close (0.05 < p ≤ 0.1)

Multivariate Cox regression analysis revealed that, for OS, FIGO stage (HR, 6.024; 95% CI, 1.961–10.258; P<0.001) and lymph node metastasis (HR, 1.703; 95% CI, 1.080–2.673; P=0.039) were significant independent prognostic factors, whilst treatment modality revealed a nonsignificant trend (HR, 1.517; 95% CI, 0.784–2.361; P=0.089) ( Table VIII ).

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did not reach statistical significanceno p-value reported

Although individual recurrence types did not reach statistical significance, the overall trend suggests that HT may provide greater locoregional control, which likely contributed to the observed improvement in PFS.

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