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Silica-calcium phosphate nanoparticles delivering recombinant influenza hemagglutinin DNA can induce long-lasting T cell immune cross-protection in mice.

Front Immunol · 2025 · PMC12188357 · PMID 40568589

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Although the Th1-polarized immune response did not reach statistical significance, both SCPs/pHAF and SCPs/pHAG formulations effectively elicited robust antigen-specific T-cell responses.

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