A recent feasibility study of intermittent fasting in patients with this disease yielded some positive signals, even though these did not reach statistical significance, maybe because the study appeared to be underpowered [ 80 ].
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A Biochemical View on Intermittent Fasting's Effects on Human Physiology-Not Always a Beneficial Strategy.
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Importantly, intermittent fasting reduces leptin levels substantially, especially when combined with physical activity [ 114 ], although there is a notable trend showing that this effect is weaker in more recent studies [ 115 ] as compared to older studies [ 116 ].