Enhanced Innate Immunity Mediated by IL-36α in Atopic Dermatitis and Differences in Cytokine Profiles of Lymphocytes in the Skin and Draining Lymph Nodes.

Biomolecules · 2025 · PMC12190923 · PMID 40563457

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showed a trendno p-value reported

Conversely, in the lymph nodes, all mouse models showed a trend toward a higher percentage of Type 1 cells in CD3+4+8a+ T cells, γδ T cells, and ILCs compared to the skin.

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an increasing trendno p-value reported

IFNγ expression was increased in IL-18Tg, while IL-4, IL-5, IL-13, and IL-17F levels also showed an increasing trend in IL-18Tg after IL-36α injection.

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