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A Systematic Review of ABCB1 Polymorphisms and Antiseizure Medication Resistance: Insights from Effect Size and Study Power Analysis.

Int J Mol Sci · 2025 · PMC12192751 · PMID 40565015

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showed a trendno p-value reported
Although not statistically significant, in forest plots, the TT genotype showed a trend toward a protective effect compared to the CC genotype (OR = 0.92, 95% CI: 0.75–1.13), suggesting it may be associated with lower odds of drug-resistant epilepsy ( Figure 15 ).

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