Barely Significant
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Evaluation of the Effects of the Sodium-Glucose Cotransporter 2 Inhibitors and Sacubitril/Valsartan Combined Therapy in Patients with HFrEF: An Echocardiographic Study.

Int J Mol Sci · 2025 · PMC12193552 · PMID 40565116

2
hedged sentences
0.1300
closest p · 2.6× alpha
0.1300
boldest claim

The sentences

did not reach statistical significancep -value = 0.13not close (p > 0.1)
Although the difference did not reach statistical significance ( p -value = 0.13), it suggests a possible trend toward a greater biomarker response in patients who tolerated up-titration.

also in 57,071 other papers

a possible trendno p-value reported
Although the difference did not reach statistical significance ( p -value = 0.13), it suggests a possible trend toward a greater biomarker response in patients who tolerated up-titration.

also in 710 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.