CalR and MPL Driver Mutations and Their Role in the Diagnosis and Clinical Course of JAK2-Unmutated Chronic Myeloproliferative Neoplasm: Results from a Pilot Single-Center Study.

Medicina (Kaunas) · 2025 · PMC12194900 · PMID 40572650

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hedged sentences

0.5100

closest p · 10.2× alpha

0.5100

boldest claim

The sentences

did not reach statistical significancep = 0.51not close (p > 0.1)

The presence of CalR Type 1 and Type 2 mutations was significantly more prevalent in patients with essential thrombocytosis (ET), although the difference did not reach statistical significance ( p = 0.51, p = 0.57).

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a possible trendno p-value reported

Our limited observations suggest a possible trend that requires confirmation. myeloproliferative disorders primary myelofibrosis essential thrombocythemia This research received no external funding. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.