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Systemic Antifolate Chemotherapy Does Not Select for Fluconazole-Resistant <i>Candida</i>: A Multicenter Clinical Study.

Pathogens · 2025 · PMC12195857 · PMID 40559582

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Although the difference did not reach statistical significance in that study, resistant isolates were observed nearly twice as frequently in MTX-treated patients compared to antifolate-naive individuals.

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