In our study, the mRNA expression of Pgc-1α exhibited an increasing trend in skeletal muscle of GB-treated mice compared to the HFD control ( Figure 6 A) and was also markedly upregulated in the palmitate-induced C2C12 myotubes following GB treatment.
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<i>Gryllus bimaculatus</i> Hydrolysate Ameliorates Obesity-Induced Muscle Atrophy by Activating Skeletal Muscle AMPK in Mice.
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Results : The low- and mid-dose GB groups showed a trend toward improved insulin resistance.