Barely Significant
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Metal-Induced Genotoxic Events: Possible Distinction Between Sporadic and Familial ALS.

Toxics · 2025 · PMC12197494 · PMID 40559965

Europe PMCDOI
2
hedged sentences
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

marginal significancep < 0.10so close (0.05 < p ≤ 0.1)
However, many reported marginal significance (0.05 < p < 0.10) or trends toward increased metal levels in ALS patients.

also in 5,069 other papers

did not reach statistical significanceno p-value reported
Several studies observed slightly elevated Co, Fe, Al, Se, and Zn in ALS-affected tissues, but the results did not reach statistical significance due to small sample sizes or measurement inconsistencies.

also in 111,027 other papers

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