The mRNA vaccine candidates with the extended Gly-rich flexible linkers had improved HAI GMTs for both antigens in the B Y A H1 dumbbell compared with their short linker counterparts, although the titer differences did not reach statistical significance.
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Development of an Influenza/COVID-19 Combination mRNA Vaccine Containing a Novel Multivalent Antigen Design That Enhances Immunogenicity of Influenza Virus B Hemagglutinins.
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