Intratumoral IL12 mRNA administration activates innate and adaptive pathways in checkpoint inhibitor-resistant tumors resulting in complete responses.

Cancer Immunol Immunother · 2025 · PMC12198101 · PMID 40560386

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showed a trendno p-value reported

The ratio of immune activating TAMs to suppressive TAMs showed a trend toward increase in all the treatment groups (Supplementary Fig.

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