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Thermoneutral housing has limited effects on social isolation-induced bone loss in male C57BL/6J mice.

JBMR Plus · 2025 · PMC12202045 · PMID 40575457

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This amelioration of isolation-induced bone loss, however, is driven in major part by a reduction in parameters within the grouped-thermoneutral mice relative to the grouped-room temperature mice, although this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.