Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications.

Front Immunol · 2025 · PMC12206644 · PMID 40589763

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did not reach statistical significanceno p-value reported

We demonstrated the applicability of SBT Treg fingerprints to polyclonal Tregs in a T1D clinical trial ( 29 ) and observed a promising trend between SBT Treg identity scores in the pre-infusion products and clinical outcome (r=0.37), although this did not reach statistical significance.

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