Cross-organ hierarchy of HLA molecular mismatches in donor-specific antibody development in solid organ transplantations.

In the living-donor kidney transplant cohort from Akita University Hospital (266 donor-recipient pairs, follow-up = 7.5 years [IQR, 3.9–11.9], event number = 7 [DR-DSA] and 14 [DQ-DSA]), the predictive power of the DR-ERS did not reach statistical significance (aHR-agen = 2.8 [95% CI, 0.7–12.0], p = 0.15) ( Figure S2 I), likely due to an insufficient number of events.

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